NOTICE OF ANNUAL MEETING OF SHAREHOLDERS OF POPULAR, INC.

The 2022 Annual Meeting of Shareholders of Popular, Inc. will be held on Thursday, May 12, 2022 at 9:00 a.m., Atlantic Standard Time, by means of remote communication, in a virtual meeting format only. Shareholders at the close of business on March 15, 2022, will be able to access the Annual Meeting by visiting www.virtualshareholdermeeting.com/BPOP2022 and entering the 16-digit control number found on their proxy card, voting instruction form, notice of internet availability of proxy materials, email or other notice previously received. For more information on how to access and participate in the meeting, please see the Popular, Inc. 2022 Proxy Statement.